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  • Product Name: SIB-1757
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

31993-01-8

31993-01-8 structure
31993-01-8 structure
  • Name: SIB 1757
  • Chemical Name: 6-methyl-2-(phenylhydrazinylidene)pyridin-3-one
  • CAS Number: 31993-01-8
  • Molecular Formula: C12H11N3O
  • Molecular Weight: 213.24
  • Catalog: Signaling Pathways GPCR/G Protein mGluR
  • Create Date: 2016-03-01 18:16:37
  • Modify Date: 2024-01-20 11:28:00
  • SIB-1757 is a highly selective and noncompetitive antagonist of mGlu5 receptor with an IC50 of 0.4 μM[1].

Name 6-methyl-2-(phenylhydrazinylidene)pyridin-3-one
Synonyms 2-Benzoazo-6-methyl-3-hydroxypyridin
6-methyl-2-phenylazo-pyridin-3-ol
Description SIB-1757 is a highly selective and noncompetitive antagonist of mGlu5 receptor with an IC50 of 0.4 μM[1].
Related Catalog
Target

human mGluR5:0.4 μM (IC50)

References

[1]. Varney MA, et al. SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5. J Pharmacol Exp Ther. 1999 Jul;290(1):170-81.

Molecular Formula C12H11N3O
Molecular Weight 213.24
Exact Mass 213.09000
PSA 57.84000
LogP 3.51100
Hazard Codes Xi
HS Code 2933399090
HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%