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3355-28-0

3355-28-0 structure
3355-28-0 structure

Name 1-bromobut-2-yne
Synonyms 2-Butynyl Bromide
1-bromanylbut-2-yne
2-Butyne, 1-bromo-
4-Bromobut-2-yne
but-2-ynyl bromide
MFCD00190233
1-Bromo-2-butyne
2-Butyne,1-bromo
1-bromo-but-2-yne
1-bromobut-2-yne
Density 1.5±0.1 g/cm3
Boiling Point 124.7±23.0 °C at 760 mmHg
Molecular Formula C4H5Br
Molecular Weight 132.986
Flash Point 36.3±17.0 °C
Exact Mass 131.957458
LogP 1.78
Vapour Pressure 15.2±0.2 mmHg at 25°C
Index of Refraction 1.490
Storage condition Flammables area
Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 1-Bromo-2-butyne
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
Flammable liquid and vapour
H226:

Section3. Composition/information on ingredients.
Ingredient name:1-Bromo-2-butyne
CAS number:3355-28-0

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels, refrigerated.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
No data
Boiling point:
Melting point:No data
Flash point:No data
Density:No data
Molecular formula:C4H5Br
Molecular weight:133.0

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, hydrogen bromide.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
UN Number:UN1993Class: 3Packing group: III
Proper shipping name: FLAMMABLE LIQUIDS, N.O.S. (1-Bromo-2-butyne)

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Symbol GHS02
GHS02
Signal Word Warning
Hazard Statements H226
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi
Risk Phrases R10
Safety Phrases S16
RIDADR UN 1993 3/PG 3
WGK Germany 3
Packaging Group III
Hazard Class 3
HS Code 2903399090

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3355-28-0

Literature: Bashiardes, George; Safir, Imad; Barbot, Francis; Laduranty, Joelle Tetrahedron Letters, 2003 , vol. 44, # 46 p. 8417 - 8420

~58%

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Literature: The Upjohn Company Patent: US4487960 A1, 1984 ;

~56%

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3355-28-0

Literature: Collingwood, Stephen P; Davies, Alan P; Golding, Bernard T Tetrahedron Letters, 1987 , vol. 28, # 38 p. 4445 - 4448

~%

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3355-28-0

Literature: Tetrahedron, , vol. 33, p. 2937 - 2948

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3355-28-0 structure

3355-28-0

Literature: Synthesis, , p. 730 - 732

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3355-28-0 structure

3355-28-0

Literature: European Journal of Medicinal Chemistry, , vol. 10, # 5 p. 507 - 513
HS Code 2903399090
Summary 2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%