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10045-52-0

10045-52-0 structure
10045-52-0 structure
  • Name: 1-(2-Phenyl-1,3-thiazol-4-yl)ethan-1-one
  • Chemical Name: 1-(2-phenyl-1,3-thiazol-4-yl)ethanone
  • CAS Number: 10045-52-0
  • Molecular Formula: C11H9NOS
  • Molecular Weight: 203.26000
  • Create Date: 2018-12-27 17:15:54
  • Modify Date: 2024-01-10 01:17:07

Name 1-(2-phenyl-1,3-thiazol-4-yl)ethanone
Synonyms 1-(2-phenylthiazol-4-yl)ethanone
5-Acetyl-2-phenylthiohydantoinsaeure
4-Acetyl-2-phenylthiazole
1-(2-Phenylthiazol-4-yl)ethanone
2-Phenyl-4-acetylthiazol
4-acetyl-2-phenyl-1,3-thiazole
1-(2-Phenyl-1,3-thiazol-4-yl)ethan-1-one
Density 1.203g/cm3
Boiling Point 353.5ºC at 760mmHg
Melting Point 84ºC
Molecular Formula C11H9NOS
Molecular Weight 203.26000
Flash Point 167.6ºC
Exact Mass 203.04000
PSA 58.20000
LogP 3.01270
Vapour Pressure 3.58E-05mmHg at 25°C
Index of Refraction 1.594
Name: 1-(2-Phenyl-1 3-thiazol-4-yl)ethan-1-one 97% Material Safety Data Sheet
Synonym: 4-Acetyl-2-phenylthiazol
CAS: 10045-52-0
Section 1 - Chemical Product MSDS Name:1-(2-Phenyl-1 3-thiazol-4-yl)ethan-1-one 97% Material Safety Data Sheet
Synonym:4-Acetyl-2-phenylthiazol

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
10045-52-0 1-(2-Phenyl-1,3-thiazol-4-yl)ethan-1-o 97% unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 10045-52-0: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: brown
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 88 - 90 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C11H9NOS
Molecular Weight: 203

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents, bases, amines.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 10045-52-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1-(2-Phenyl-1,3-thiazol-4-yl)ethan-1-one - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 10045-52-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 10045-52-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 10045-52-0 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Hazard Codes Xi: Irritant;
Safety Phrases S24/25
HS Code 2934100090

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Literature: BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITÉ DE MONTRÉAL; BANVILLE, Jacques; RÉMILLARD, Roger; RUEDIGER, Edward H.; DEON, Daniel H.; GAGNON, Marc; DUBÉ, Laurence; GUY, Julia; PRIESTLEY, Eldon Scott; POSY, Shoshana L.; MAXWELL, Brad D.; WONG, Pancras C. Patent: WO2013/163279 A1, 2013 ; Location in patent: Paragraph 00219 ;

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10045-52-0

Literature: Sarodnick; Kempter Pharmazie, 1983 , vol. 38, # 12 p. 829 - 832

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10045-52-0

Literature: Shafiee, A.; Anaraki, M.; Bazzaz, A. Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 3 p. 861 - 864

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Literature: Chemische Berichte, , vol. 97, p. 1915 - 1920

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Literature: Chemische Berichte, , vol. 97, p. 1915 - 1920

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Literature: WO2013/163279 A1, ;

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Literature: WO2013/163279 A1, ;

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10045-52-0

Literature: WO2013/163279 A1, ;
HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%