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593-70-4

593-70-4 structure
593-70-4 structure

Name Chlorofluoromethane
Synonyms monofluoro boroxine
monofluorobenzene
4-fluorobenzene
Monofluorboroxin
1-fluorobenzene
p-fluorobenzene
monofluorochloromethane
2-fluorobenzene
Chlorofluoromethane
o-di-fluorobenzene
FLUOROBOROXIN
Fluorochloromethane
monochloromonofluoromethane
Chloro(fluoro)methane
Methane, chlorofluoro-
Density 1.1±0.1 g/cm3
Boiling Point -10.8±8.0 °C at 760 mmHg
Melting Point -133ºC
Molecular Formula CH2ClF
Molecular Weight 68.478
Flash Point -89.8±5.3 °C
Exact Mass 67.982903
LogP 0.78
Vapour Pressure 2603.0±0.0 mmHg at 25°C
Index of Refraction 1.304

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PA6408000
CHEMICAL NAME :
Methane, chlorofluoro-
CAS REGISTRY NUMBER :
593-70-4
BEILSTEIN REFERENCE NO. :
1730796
LAST UPDATED :
199801
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C-H2-Cl-F
MOLECULAR WEIGHT :
68.48
WISWESSER LINE NOTATION :
G1F

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12635 mg/m3
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
10000 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10000 ppm/6H/2W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes Endocrine - other changes Blood - changes in spleen
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
78 gm/kg/1Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
10 pph
REFERENCE :
EVSRBT Environmental Science Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.1- 1972- Volume(issue)/page/year: 25,91,1982 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,229,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,229,1986 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993 OEL-HUNGARY:TWA 100 mg/m3;STEL 200 mg/m3 JAN 1993 OEL-SWITZERLAND;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3008 No. of Facilities: 262 (estimated) No. of Industries: 5 No. of Occupations: 5 No. of Employees: 2705 (estimated) No. of Female Employees: 159 (estimated)
RIDADR UN 3163
Hazard Class 2.2