35803-45-3

35803-45-3 structure

35803-45-3 structure

Name: Uracil-13C
Chemical Name: 1H-pyrimidine-2,4-dione-13C
CAS Number: 35803-45-3
Molecular Formula: C₄H₄N₂O₂
Molecular Weight: 113.07900
Catalog: Research Areas Cancer
Create Date: 2018-03-29 08:00:00
Modify Date: 2024-01-10 16:16:50
Uracil-13C is the 13C labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].

Name	1H-pyrimidine-2,4-dione-13C
Synonyms	Uracil-2-13C Uracil (2-13C) (JAN) 2-[(13)C]uracil MFCD00084096

Description	Uracil-13C is the 13C labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
Related Catalog	Research Areas >> Cancer
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Pałasz A, et al. In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications. Eur J Med Chem. 2015 Jun 5;97:582-611.

Density	1.322g/cm3
Melting Point	>300ºC (dec.)(lit.)
Molecular Formula	C₄H₄N₂O₂
Molecular Weight	113.07900
Exact Mass	113.03100
PSA	65.72000
Index of Refraction	1.502

RIDADR	NONH for all modes of transport
WGK Germany	3

58069-82-2 structure

58069-82-2

471-25-0 structure

471-25-0

~65%

35803-45-3 structure

35803-45-3

Literature: Iida, Katsumi; Chiyoda, Takeshi; Hirasawa, Ryo; Iwata, Akiko; Kajiwara, Masahiro Journal of Labelled Compounds and Radiopharmaceuticals, 1997 , vol. 39, # 1 p. 69 - 77

Precursor 2
58069-82-2 471-25-0
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