34444-01-4

34444-01-4 structure

Name: Cefamandole
Chemical Name: cefamandole
CAS Number: 34444-01-4
Molecular Formula: C₁₈H₁₈N₆O₅S₂
Molecular Weight: 462.50300
Catalog: API Antibiotics Cephalosporin
Create Date: 2018-07-09 14:35:18
Modify Date: 2024-01-02 10:16:39
Cefamandole is a second-generation broad-spectrum cephalosporin antibiotic. As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia.

Name	cefamandole
Synonyms	cefamandol MFCD00056872 7-[(2-Hydroxy-2-phenylacetyl)amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Florfenicol-d3 AMine CEFAMANDOLE cephadole cephamandole cefadole EINECS 252-030-0

Description	Cefamandole is a second-generation broad-spectrum cephalosporin antibiotic. As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection

CHEMICAL NAME :: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-3- (((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-(6-alpha,7-beta(R*)))-

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 30,660,1980 ** REPRODUCTIVE DATA **

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 8,280,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3194 No. of Facilities: 299 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 16094 (estimated) No. of Female Employees: 13604 (estimated)