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72-80-0

72-80-0 structure
72-80-0 structure

Name chlorquinaldol
Synonyms 5,7-Dichloro-2-methyl-8-quinolinol
5,7-Dichloro-8-hydroxyquinaldine
2-methyl-5,7-dichloro-8-hydroxyquinoline
5,7-Dichloro-8-quinaldinol
Clorquinaldol
Chloroquinaldol
EINECS 200-789-3
Gynotherax
5,7-dichloro-2-methylquinolin-8-ol
2-methylchloroxine
5,7-Dichlor-2-methylchinolin-8-ol
Saprosan
Sterosan
5,7-dichloro-2-methyl-8-hydroxy-quinoline
8-Quinolinol, 5,7-dichloro-2-methyl-
chlorquinaldol
Chlorchinaldolum
Chlorquinaldolum
MFCD00023984
Description Chlorquinaldol is a mono-hydroxyquinoline, is an antifungal and antibacterial, used for topical treatment of skin conditions and vaginal infections.
Related Catalog
Density 1.5±0.1 g/cm3
Boiling Point 350.7±37.0 °C at 760 mmHg
Melting Point 108-112 °C (dec.)(lit.)
Molecular Formula C10H7Cl2NO
Molecular Weight 228.075
Flash Point 165.9±26.5 °C
Exact Mass 226.990463
PSA 33.12000
LogP 4.21
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.679
Storage condition 2-8°C
Water Solubility Insoluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VC5600000
CHEMICAL NAME :
8-Quinolinol, 5,7-dichloro-2-methyl-
CAS REGISTRY NUMBER :
72-80-0
BEILSTEIN REFERENCE NO. :
0156683
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H7-Cl2-N-O
MOLECULAR WEIGHT :
228.08
WISWESSER LINE NOTATION :
T66 BNJ C1 GG IG JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
2250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Sex chromosome loss and nondisjunction
TEST SYSTEM :
Mold - Aspergillus nidulans
DOSE/DURATION :
1 gm/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 26,159,1974
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36-S36/37/39
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS VC5600000
HS Code 2933499090

~62%

72-80-0 structure

72-80-0

Literature: Organic Letters, , vol. 16, # 3 p. 864 - 867

~%

72-80-0 structure

72-80-0

Literature: CH229982 , ;
Precursor  2

DownStream  0

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%