152068-09-2
152068-09-2 structure
- Name: Oxazole yellow
- Chemical Name: Yo-Pro-1
- CAS Number: 152068-09-2
- Molecular Formula: C24H29I2N3O
- Molecular Weight: 629.32
- Catalog: Research Areas Others
- Create Date: 2017-08-12 21:20:34
- Modify Date: 2022-01-30 09:28:24
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YO-PRO-1 (Oxazole yellow) is a carbocyanine monomer and DNA green fluorescent dye that is not permeable to normal animal cell membranes but is permeable to the cell membranes of apoptotic and necrotic cells. YO-PRO-1 is commonly used for the detection of apoptosis and necrosis. YO-PRO-1 has a high affinity for DNA and is essentially non-fluorescent when not bound to DNA. When apoptosis occurs, the permeability of the cell membrane changes. YO-PRO-1 can enter apoptotic cells and bind to DNA and emit bright green fluorescence. Therefore, YO-PRO-1 is often used together with propidium iodide (PI) to analyze and identify apoptotic and necrotic cells.
| Name | Yo-Pro-1 |
|---|---|
| Synonyms | trimethyl-[3-[4-[(Z)-(3-methyl-1,3-benzoxazol-2-ylidene)methyl]quinolin-1-ium-1-yl]propyl]azanium,diiodide |
| Description | YO-PRO-1 (Oxazole yellow) is a carbocyanine monomer and DNA green fluorescent dye that is not permeable to normal animal cell membranes but is permeable to the cell membranes of apoptotic and necrotic cells. YO-PRO-1 is commonly used for the detection of apoptosis and necrosis. YO-PRO-1 has a high affinity for DNA and is essentially non-fluorescent when not bound to DNA. When apoptosis occurs, the permeability of the cell membrane changes. YO-PRO-1 can enter apoptotic cells and bind to DNA and emit bright green fluorescence. Therefore, YO-PRO-1 is often used together with propidium iodide (PI) to analyze and identify apoptotic and necrotic cells. |
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| Related Catalog |
| Molecular Formula | C24H29I2N3O |
|---|---|
| Molecular Weight | 629.32 |
| Exact Mass | 629.04000 |
| PSA | 23.00000 |
| Hazard Codes | T+ |
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