100900-19-4

100900-19-4 structure

Name: NA-CBZ-ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE
Chemical Name: acetic acid,benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methoxynaphthalen-2-yl)amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
CAS Number: 100900-19-4
Molecular Formula: C₃₃H₄₅N₉O₇
Molecular Weight: 679.76600
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cathepsin
Create Date: 2017-11-13 04:10:22
Modify Date: 2024-01-08 11:01:07
Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λex = 355 nm, λem = 430 nm)[1][2].

Name	acetic acid,benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methoxynaphthalen-2-yl)amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Synonyms	Z-Arg-Arg 4-methoxy-\|A-naphthylamide acetate salt

Description	Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λex = 355 nm, λem = 430 nm)[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
Target	Cathepsin B
References	[1]. Büth H, et al. HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration. Eur J Cell Biol. 2004 Dec;83(11-12):781-95. [2]. van den Bos T, et al. Differences in matrix composition between calvaria and long bone in mice suggest differences in biomechanical properties and resorption: Special emphasis on collagen. Bone. 2008 Sep;43(3):459-68.

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H351
Precautionary Statements	P281
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xn: Harmful;
Risk Phrases	40
Safety Phrases	22-36
RIDADR	NONH for all modes of transport