34604-52-9
34604-52-9 structure
- Name: Ms-PEG2-Ms
- Chemical Name: 2-(2-methylsulfonyloxyethoxy)ethyl methanesulfonate
- CAS Number: 34604-52-9
- Molecular Formula: C6H14O7S2
- Molecular Weight: 262.30100
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-08-08 02:38:27
- Modify Date: 2024-01-06 07:48:37
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Ms-PEG2-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-(2-methylsulfonyloxyethoxy)ethyl methanesulfonate |
|---|---|
| Synonyms |
oxydiethane-2,1-diyl dimethanesulfonate
diethyleneglycol bis-methane-sulfonyl ester dimethyl 3-oxapentane-1,5-disulfonate di-mesyl-diglyme Diethylene Glycol Dimesylate 2,2'-Oxybis-ethanol Dimethanesulfonate |
| Description | Ms-PEG2-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.389g/cm3 |
|---|---|
| Boiling Point | 480.2ºC at 760 mmHg |
| Molecular Formula | C6H14O7S2 |
| Molecular Weight | 262.30100 |
| Flash Point | 244.2ºC |
| Exact Mass | 262.01800 |
| PSA | 112.73000 |
| LogP | 1.11700 |
| Index of Refraction | 1.47 |
| Hazard Codes | T+ |
|---|---|
| HS Code | 2904100000 |
|
~94%
34604-52-9 |
| Literature: Catalysis Communications, , vol. 21, p. 96 - 103 |
| Precursor 2 | |
|---|---|
| DownStream 10 | |
| HS Code | 2904100000 |
|---|---|
| Summary | 2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |