Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Formestane
Price: ￥568.0/5g ￥168.0/1g
Purity: 99.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Formestane
Price: $300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

566-48-3

566-48-3 structure

566-48-3 structure

Name: Formestane
Chemical Name: formestane
CAS Number: 566-48-3
Molecular Formula: C₁₉H₂₆O₃
Molecular Weight: 302.408
Catalog: API Antineoplastic agents Hormone antineoplastic agents
Create Date: 2018-06-03 08:00:00
Modify Date: 2024-01-02 23:31:25

Name	formestane
Synonyms	Androst-4-ene-3,17-dione, 4-hydroxy- 4-Hydroxyandrost-4-ene-3,17-dione 4-Hydroxy-4-androstene-3,17-dione Formestane B,Aromatase inhibitor Lentaron 4-androsten-4-ol-3,17-dione 4-Hydroxyandrostenedione 4-OH-A MFCD00057814 (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione

Density	1.2±0.1 g/cm3
Boiling Point	475.4±45.0 °C at 760 mmHg
Melting Point	199-202°C
Molecular Formula	C₁₉H₂₆O₃
Molecular Weight	302.408
Flash Point	255.4±25.2 °C
Exact Mass	302.188202
PSA	54.37000
LogP	2.66
Vapour Pressure	0.0±2.7 mmHg at 25°C
Index of Refraction	1.570
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BV8152500

CHEMICAL NAME :: Androst-4-ene-3,17-dione, 4-hydroxy-

CAS REGISTRY NUMBER :: 566-48-3

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H26-O3

MOLECULAR WEIGHT :: 302.45

WISWESSER LINE NOTATION :: L E5 B666 FV OV MUTJ A1 E1 NQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 182 mg/kg

SEX/DURATION :: female 3-5 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - parturition

REFERENCE :: JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939- Volume(issue)/page/year: 118,93,1988

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 136 mg/kg

SEX/DURATION :: female 2-4 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects

REFERENCE :: JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939- Volume(issue)/page/year: 118,93,1988

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 120 mg/kg

SEX/DURATION :: female 11-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral

REFERENCE :: ECJPAE Endocrinologia Japonica. (Japan Pub. Trading Co., Ltd., POB 5030, Tokyo International, Tokyo, Japan) V.1- 1954- Volume(issue)/page/year: 36,29,1989

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 250 mg/kg

SEX/DURATION :: female 3-7 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :: ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 100,1684,1977

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H360
Precautionary Statements	P201-P308 + P313
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T:Toxic
Risk Phrases	R60
Safety Phrases	S53-S36/37/39-S45
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	BV8152500