Name | l-leucine-2-d1 |
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Synonyms |
homoserine lactone*HBr
(S)-2-[2H1]-Leu L-homoserine lactone hydrobromide (S)-2-amino-2-deuterio-4-methyl-pentanoic acid L-homoserine lactone HBr (S)-3-Aminodihydrofuran-2(3H)-one hydrobromide |
Description | L-Leucine-d1 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. |
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Related Catalog | |
In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
References |
Melting Point | >300 °C(lit.) |
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Molecular Formula | C6H12DNO2 |
Molecular Weight | 132.17900 |
Exact Mass | 132.10100 |
PSA | 63.32000 |
LogP | 1.14470 |
~86% 89836-93-1 |
Literature: Mitulovi, Goran; Laemmerhofer, Michael; Maier; Lindner, Wolfgang Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 5 p. 449 - 461 |
~62% 89836-93-1 |
Literature: Faleev, N. G.; Ruvinov, S. B.; Saporovskaya, M. B.; Belikov, V. M.; Zakomyrdina, L. N.; et al. Tetrahedron Letters, 1990 , vol. 31, # 48 p. 7051 - 7054 |
~% 89836-93-1 |
Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 43, # 5 p. 449 - 461 |
~% 89836-93-1 |
Literature: Bulletin of the Chemical Society of Japan, , vol. 56, # 12 p. 3652 - 3656 |
~% 89836-93-1 |
Literature: Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 38, # 10 p. 2154 - 2156 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 10 p. 2341 - 2343 |
~% 89836-93-1 |
Literature: Organic and Biomolecular Chemistry, , vol. 9, # 23 p. 7983 - 7985 |
Precursor 5 | |
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DownStream 0 |