330676-02-3

330676-02-3 structure

Name: KH 7
Chemical Name: 2-(1H-benzimidazol-2-ylsulfanyl)-N'-[(3-bromo-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]propanehydrazide
CAS Number: 330676-02-3
Molecular Formula: C₁₇H₁₅BrN₄O₂S
Molecular Weight: 419.296
Catalog: Research Areas Others
Create Date: 2017-02-17 15:51:02
Modify Date: 2024-01-07 15:05:21
KH7 is a soluble adenylyl cyclase (sAC)-specific inhibitor, with IC50s of 3-10 μM toward both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays[1].

Name	2-(1H-benzimidazol-2-ylsulfanyl)-N'-[(3-bromo-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]propanehydrazide
Synonyms	Propanoic acid, 2-(1H-benzimidazol-2-ylthio)-, 2-[(1E)-(5-bromo-2-hydroxyphenyl)methylene]hydrazide 2-(1H-Benzimidazol-2-ylsulfanyl)-N'-[(E)-(5-bromo-2-hydroxyphenyl)methylene]propanehydrazide MNI-caged-L-glutamate KH7 (E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N'-(5-bromo-2-hydroxybenzylidene)propanehydrazide

Description	KH7 is a soluble adenylyl cyclase (sAC)-specific inhibitor, with IC50s of 3-10 μM toward both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	IC50: 3-10 μM (recombinant sACt)[1].
References	[1]. Hess KC, et al. The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization. Dev Cell. 2005 Aug;9(2):249-59.