1191-85-1

1191-85-1 structure

Name: 5,8,11,14-Icosatetraynoic acid
Chemical Name: icosa-5,8,11,14-tetraynoic acid
CAS Number: 1191-85-1
Molecular Formula: C₂₀H₂₄O₂
Molecular Weight: 296.403
Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
Create Date: 2018-05-12 08:00:00
Modify Date: 2024-01-02 10:23:05
Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively)[1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 µM[2].

Name	icosa-5,8,11,14-tetraynoic acid
Synonyms	Eicosa-5,8,11,14-tetrainsaeure MFCD00036967 5,8,11,14-eicosatetrayonic acid 5,8,11,14-Icosatetraynoic acid 5,8,11,14-Eicosatetraynoic acid ETYA Icosa-5,8,11,14-tetraynoic acid Octadehydroarachidonic acid eicosatetraynoic acid

Description	Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively)[1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 µM[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX:8 μM (ID50)
References	[1]. Hammarström S, et al. Selective inhibition of platelet n-8 lipoxygenase by 5,8,11-eicosatriynoic acid. Biochim Biophys Acta. 1977 Jun 22;487(3):517-9. [2]. Kliewer SA, et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell. 1995 Dec 1;83(5):813-9.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
HS Code	2916190090

HS Code	2916190090
Summary	2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%