565226-18-8

565226-18-8 structure

Name: 3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine
Chemical Name: 5-iodo-3',5'-diacetyl-2'-fluoro-2'-deoxyuridine
CAS Number: 565226-18-8
Molecular Formula: C₁₃H₁₄FIN₂O₇
Molecular Weight: 456.16
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-09-04 03:13:07
Modify Date: 2024-01-15 21:10:43
3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-iodo-3',5'-diacetyl-2'-fluoro-2'-deoxyuridine
Synonyms	3'',5''-diacetyl-5-iodo-2''-fluoro-2''-deoxyuridine

Description	3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.