CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
AV1645000
-
CHEMICAL NAME :
-
Adipic acid, dimethyl ester
-
CAS REGISTRY NUMBER :
-
627-93-0
-
BEILSTEIN REFERENCE NO. :
-
1707443
-
LAST UPDATED :
-
199712
-
DATA ITEMS CITED :
-
8
-
MOLECULAR FORMULA :
-
C8-H14-O4
-
MOLECULAR WEIGHT :
-
174.22
-
WISWESSER LINE NOTATION :
-
1OV4VO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
1809 uL/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
REFERENCE :
-
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,1596,1973 ** REPRODUCTIVE DATA **
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
DOSE :
-
362 mg/kg
-
SEX/DURATION :
-
female 5-15 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
-
REFERENCE :
-
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,1596,1973
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
DOSE :
-
181 mg/kg
-
SEX/DURATION :
-
female 5-15 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
-
REFERENCE :
-
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,1596,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1493 No. of Facilities: 2425 (estimated) No. of Industries: 18 No. of Occupations: 25 No. of Employees: 24766 (estimated) No. of Female Employees: 3381 (estimated)
|