123-08-0

123-08-0 structure

Name: 4-hydroxybenzaldehyde
Chemical Name: 4-hydroxybenzaldehyde
CAS Number: 123-08-0
Molecular Formula: C₇H₆O₂
Molecular Weight: 122.121
Catalog: Organic raw materials Carboxylic compounds and derivatives Cyclic carboxylic acid
Create Date: 2018-02-05 08:00:00
Modify Date: 2024-01-01 23:23:50
p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.

Name	4-hydroxybenzaldehyde
Synonyms	p-Hydroxybenzaldehyde MFCD00006939 4-Hydroxy benzaldehyde 4-Hydroxybenzaldehyde EINECS 204-599-1 Bisoprolol Impurity 15

Description	p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor Natural Products >> Acids and Aldehydes Research Areas >> Neurological Disease
Target	Human Endogenous Metabolite
In Vitro	p-Hydroxybenzaldehyde (4-hydroxybenzaldehyde) is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. p-Hydroxybenzaldehyde (101.7 μM) significantly reduces the GABA-induced chloride current of GABAA receptors expressed on Xenopus oocytes[1].
References	[1]. Zhang J, et al. The Effect of 4-hydroxybenzaldehyde on the γ-aminobutyric Acid Type A Receptor. Malays J Med Sci. 2017 Mar;24(2):94-99.

TOXIC EFFECTS :: Behavioral - hallucinations, distorted perceptions Behavioral - tremor Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	CU6475000
Packaging Group	I; II; III
HS Code	2912210000

HS Code	2912499000
Summary	2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%