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2954-50-9

2954-50-9 structure
2954-50-9 structure
  • Name: 2-Aminotetralin
  • Chemical Name: 1,2,3,4-tetrahydro-2-naphthylamine
  • CAS Number: 2954-50-9
  • Molecular Formula: C10H13N
  • Molecular Weight: 147.217
  • Create Date: 2018-03-24 08:00:00
  • Modify Date: 2024-01-09 16:07:56

Name 1,2,3,4-tetrahydro-2-naphthylamine
Synonyms 1-Naphthalenol,1,2,3,4-tetrahydro-,benzoate
1-Benzoyloxy-1.2.3.4-tetrahydro-naphthalin
1,2,3,4-tetrahydronaphth-2-ylamine
2-Aminotetralin
Aminotetralin
1,2,3,4-tetrahydronaphthalen-1-yl benzoate
2-amino-1,2,3,4-tetrahydronaphthalene
1,2,3,4-Tetrahydro-2-naphthalenamine
2-amino-tetralin
2-R-amino-tetraline
2-Naphthalenamine, 1,2,3,4-tetrahydro-
1,2,3,4-tetrahydro-1-naphthyl benzoate
THN
1,2,3,4-Tetrahydronaphthalen-2-amine
1,2,3,4-tetrahydro-naphth-1-yl benzoate
Density 1.0±0.1 g/cm3
Boiling Point 250.7±29.0 °C at 760 mmHg
Melting Point 149-151 °C
Molecular Formula C10H13N
Molecular Weight 147.217
Flash Point 111.6±19.6 °C
Exact Mass 147.104797
PSA 26.02000
LogP 2.09
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.561

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QM4900000
CHEMICAL NAME :
2-Naphthylamine, 1,2,3,4-tetrahydro-
CAS REGISTRY NUMBER :
2954-50-9
BEILSTEIN REFERENCE NO. :
1102357
LAST UPDATED :
199612
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C10-H13-N
MOLECULAR WEIGHT :
147.24
WISWESSER LINE NOTATION :
L66&TJ HZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,466,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,466,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Human
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - sleep Behavioral - hallucinations, distorted perceptions
REFERENCE :
APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher information, see VAAPB7. Volume(issue)/page/year: 115,14,1889
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Human
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - sleep Behavioral - hallucinations, distorted perceptions
REFERENCE :
APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher information, see VAAPB7. Volume(issue)/page/year: 115,14,1889
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
64 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 61,168,1965
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Vascular - regional or general arteriolar constriction Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 35,70,1928
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher information, see VAAPB7. Volume(issue)/page/year: 115,14,1889
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 61,168,1965
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
375 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher information, see VAAPB7. Volume(issue)/page/year: 115,14,1889 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
DOSE :
20 mg/kg
SEX/DURATION :
female 5 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Newborn - stillbirth
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 100,555,1959
Risk Phrases R36/37/38
Safety Phrases 26-36/37/39
HS Code 2921450090
HS Code 2921450090
Summary 2921450090 1-naphthylamine (α-naphthylamine), 2-naphthylamine (β-naphthylamine) and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%