612530-44-6

612530-44-6 structure

Name: 5-Phenyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide
Chemical Name: 5-Phenyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide
CAS Number: 612530-44-6
Molecular Formula: C₈H₈N₂O₃S
Molecular Weight: 212.22600
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2018-06-11 10:16:39
Modify Date: 2024-01-11 06:17:05
PTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 1.6 mM; 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for derivatives synthesis.

Name	5-Phenyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide
Synonyms	PTP1B-IN-1

Description	PTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 1.6 mM; 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for derivatives synthesis.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Metabolic Disease
References	[1]. Black E, et al. Structure-based design of protein tyrosine phosphatase-1B inhibitors. Bioorg Med Chem Lett. 2005 May 16;15(10):2503-7. [2]. Vintonyak VV, et al. Using small molecules to target protein phosphatases. Bioorg Med Chem. 2011 Apr 1;19(7):2145-55.