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Related CAS#:

7681-76-7

7681-76-7 structure
7681-76-7 structure
  • Name: Ronidazole
  • Chemical Name: (1-methyl-5-nitroimidazol-2-yl)methyl carbamate
  • CAS Number: 7681-76-7
  • Molecular Formula: C6H8N4O4
  • Molecular Weight: 200.152
  • Catalog: analytical chemistry Standard Life science standard
  • Create Date: 2018-08-04 12:06:48
  • Modify Date: 2024-01-02 15:35:50
  • Ronidazole is an antiprotozoal agent.Target: AntiparasiticRonidazole is an antiprotozoal agent used in veterinary medicine. It may also have use for the treatment of Tritrichomonas foetus infection in cats. Ronidazole kills T foetus at concentrations > 0.1 μg/mL in vitro. Ronidazole (30 or 50 mg/kg) cures T foetus infection for follow-up durations of 21 to 30 weeks after treatment in 10/10 cats [1].

Name (1-methyl-5-nitroimidazol-2-yl)methyl carbamate
Synonyms (1-Methyl-5-nitro-1H-imidazol-2-yl)methyl carbamate
Ridazole
Carbamic Acid (1-Methyl-5-nitroimidazol-2-yl)methyl Ester
Ridzol P
Dugro
(1-Methyl-5-nitroimidazole-2-yl)methyl Carbamate
2-Carbamoyloxymethyl-1-methyl-5-nitro-imidazol
1-Methyl-2-[(carbamoyloxy)methyl]-5-nitroimidazole
Ridzol
1-Methyl-5-nitroimidazole-2-methanol Carbamate (Ester)
1H-Imidazole-2-methanol, 1-methyl-5-nitro-, carbamate (ester)
MCMN
2-carbamoyloxymethyl-1-methyl-5-nitro-1H-imidazole
Ronidazole
Ronidazol
EINECS 231-675-1
Description Ronidazole is an antiprotozoal agent.Target: AntiparasiticRonidazole is an antiprotozoal agent used in veterinary medicine. It may also have use for the treatment of Tritrichomonas foetus infection in cats. Ronidazole kills T foetus at concentrations > 0.1 μg/mL in vitro. Ronidazole (30 or 50 mg/kg) cures T foetus infection for follow-up durations of 21 to 30 weeks after treatment in 10/10 cats [1].
Related Catalog
References

[1]. Lim, S., et al., Efficacy of ronidazole for treatment of cats experimentally infected with a Korean isolate of Tritrichomonas foetus. Korean J Parasitol, 2012. 50(2): p. 161-4.

Density 1.7±0.1 g/cm3
Boiling Point 502.3±30.0 °C at 760 mmHg
Melting Point 167-169°
Molecular Formula C6H8N4O4
Molecular Weight 200.152
Flash Point 257.6±24.6 °C
Exact Mass 200.054550
PSA 115.96000
LogP -0.45
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.651
Storage condition −20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NI6803000
CHEMICAL NAME :
Imidazole-2-methanol, 1-methyl-5-nitro-, carbamate (ester)
CAS REGISTRY NUMBER :
7681-76-7
BEILSTEIN REFERENCE NO. :
0886221
LAST UPDATED :
199612
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C6-H8-N4-O4
MOLECULAR WEIGHT :
200.18
WISWESSER LINE NOTATION :
T5N CNJ A1 B1OVZ ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,289,1976
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS NI6803000
HS Code 2933290090
Precursor  0

DownStream  1

HS Code 2933290090
Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%