82896-38-6

82896-38-6 structure

Name: Pyridoxine-d5 hydrochloride
Chemical Name: 3,4-Pyridinedimethan-α3,α3-d2-ol, 5-hydroxy-6-(methyl-d3)-, hydrochloride
CAS Number: 82896-38-6
Molecular Formula: C₈H₁₂ClNO₃
Molecular Weight: 205.63900
Catalog: Signaling Pathways NF-κB Keap1-Nrf2
Create Date: 2017-10-30 16:05:50
Modify Date: 2024-01-14 19:49:54
Pyridoxine-d5 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride[1]. Pyridoxine hydrochloride (Pyridoxol;Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol;Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway[2].

Name	3,4-Pyridinedimethan-α3,α3-d2-ol, 5-hydroxy-6-(methyl-d3)-, hydrochloride
Synonyms	Pyridoxine Hydrochloride D5

Description	Pyridoxine-d5 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride[1]. Pyridoxine hydrochloride (Pyridoxol;Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol;Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway[2].
Related Catalog	Signaling Pathways >> NF-κB >> Keap1-Nrf2
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Li C, et al. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Cell Mol Biol (Noisy-le-grand). 2018 Jul 30;64(10):119-124.