64725-24-2

64725-24-2 structure

Name: Bouvardin,5-(N-methyl-L-tyrosine)- (9CI)
Chemical Name: deoxyBouvardin
CAS Number: 64725-24-2
Molecular Formula: C₄₀H₄₈N₆O₉
Molecular Weight: 756.84400
Catalog: Signaling Pathways Apoptosis c-Myc
Create Date: 2017-02-21 09:10:37
Modify Date: 2024-01-10 13:16:22
RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways.

Name	deoxyBouvardin
Synonyms	Desoxybenzoin-semicarbazon 1,2-diphenyl-ethanone semicarbazone Semicarbazon des Phenyl-benzyl-ketons deoxybouvadin Benzyl-phenyl-keton-semicarbazon 1,2-Diphenyl-1-semicarbazonoethan deoxybenzoin semicarbazone

Description	RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Wnt Signaling Pathways >> Stem Cell/Wnt >> Notch Signaling Pathways >> Apoptosis >> c-Myc
Target	IC50: 50 ng/mL (Wnt); 75 ng/mL (Myc), 93 ng/mL (Notch)[1]
In Vivo	RA-V 对 Wnt、Myc 和 Notch 具有活性，IC50 值分别为 50、75 和 93 ng/mL[1]。
References	[1]. Premalatha Balachandran, et al. Crosstalk of Cancer Signaling Pathways by Cyclic Hexapeptides and Anthraquinones from Rubia cordifolia. Molecules. 2021 Jan 31;26(3):735.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 32,3216,1984

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 32,3216,1984