- BioBioPha
- China
- Product Name: Licochalcone B
- Price: ￥Inquiry/10mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Licochalcone B
- Price: ￥2188.0/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Licochalcone B
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
58749-23-8
58749-23-8 structure
- Name: Licochalcone B
- Chemical Name: (E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
- CAS Number: 58749-23-8
- Molecular Formula: C16H14O5
- Molecular Weight: 286.279
- Catalog: Biochemical Plant extracts
- Create Date: 2018-09-23 07:22:55
- Modify Date: 2024-01-04 12:44:21
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Licochalcone B is an extract from the root of Glycyrrhiza inflate. Licochalcone B inhibits amyloid β (Aβ42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ions[1].
| Name | (E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one |
|---|---|
| Synonyms |
2-methoxy-3,4,4'-trihydroxychalcone
Licochalcone B Licochalcon B (2E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one 2-Propen-1-one, 3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)- licochalcone |
| Description | Licochalcone B is an extract from the root of Glycyrrhiza inflate. Licochalcone B inhibits amyloid β (Aβ42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ions[1]. |
|---|---|
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 550.5±50.0 °C at 760 mmHg |
| Melting Point | 196-197ºC |
| Molecular Formula | C16H14O5 |
| Molecular Weight | 286.279 |
| Flash Point | 208.5±23.6 °C |
| Exact Mass | 286.084137 |
| PSA | 86.99000 |
| LogP | 2.57 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.684 |
| Storage condition | 2-8C |
|
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58749-23-8 |
| Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
|
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58749-23-8 |
| Literature: Islam, Azizul; Khan, Saeed Ahmad; Krishnamurti, M. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 10 p. 965 - 966 |
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58749-23-8 |
| Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
|
~%
58749-23-8 |
| Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
|
~%
58749-23-8 |
| Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
|
~%
58749-23-8 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 1 p. 181 - 185 |
| Precursor 6 | |
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| DownStream 0 | |