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130727-44-5

130727-44-5 structure
130727-44-5 structure
  • Name: Thiol-C9-PEG7
  • Chemical Name: 2-[2-[2-[2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  • CAS Number: 130727-44-5
  • Molecular Formula: C23H48O7S
  • Molecular Weight: 468.68800
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-12-27 17:40:23
  • Modify Date: 2024-01-04 12:53:28
  • Thiol-C9-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-[2-[2-[2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonyms MUHEG
3,6,9,12,15,18-Hexaoxanonacosan-1-ol,29-mercapto
Thiol-C9-PEG7
Description Thiol-C9-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.023g/cm3
Boiling Point 550.4ºC at 760mmHg
Molecular Formula C23H48O7S
Molecular Weight 468.68800
Flash Point 286.7ºC
Exact Mass 468.31200
PSA 114.41000
LogP 3.51900
Vapour Pressure 0mmHg at 25°C
Index of Refraction n20/D 1.474
RIDADR NONH for all modes of transport