Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Benzoic acid,2-(acetyloxy)-5-bromo-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1503-53-3

1503-53-3 structure

Name: Benzoic acid,2-(acetyloxy)-5-bromo-
Chemical Name: 2-acetyloxy-5-bromobenzoic acid
CAS Number: 1503-53-3
Molecular Formula: C₉H₇BrO₄
Molecular Weight: 259.05300
Create Date: 2018-09-16 13:26:26
Modify Date: 2024-01-02 10:14:59

Name	2-acetyloxy-5-bromobenzoic acid
Synonyms	5-bromo-2-acetoxybenzoic acid 5-Bromosalicylic acid acetate 2-Acetoxy-5-brom-benzoesaeure 5-Bromo-2-acetylsalicylic acid 5-bromoaspirin 5-Bromoacetylsalicylic acid 2-Acetoxy-5-bromobenzoic acid Sedasprin Bromoaspirin acetyl-5-bromosalicylic acid

Density	1.662g/cm3
Boiling Point	368.4ºC at 760mmHg
Melting Point	60 °C
Molecular Formula	C₉H₇BrO₄
Molecular Weight	259.05300
Flash Point	176.6ºC
Exact Mass	257.95300
PSA	63.60000
LogP	2.07260
Vapour Pressure	4.46E-06mmHg at 25°C
Index of Refraction	1.585

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VO1870000

CHEMICAL NAME :: Salicylic acid, 5-bromo-, acetate

CAS REGISTRY NUMBER :: 1503-53-3

BEILSTEIN REFERENCE NO. :: 2695058

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H7-Br-O4

MOLECULAR WEIGHT :: 259.07

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1130 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: CRAAA7 Current Researches in Anesthesia and Analgesia. (Cleveland, OH) V.1-35, 1922-56. For publisher information, see AACRAT. Volume(issue)/page/year: 25,221,1946

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 650 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: CRAAA7 Current Researches in Anesthesia and Analgesia. (Cleveland, OH) V.1-35, 1922-56. For publisher information, see AACRAT. Volume(issue)/page/year: 25,221,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 16800 mg/kg/8W-C

TOXIC EFFECTS :: Musculoskeletal - other changes Related to Chronic Data - death

REFERENCE :: CRAAA7 Current Researches in Anesthesia and Analgesia. (Cleveland, OH) V.1-35, 1922-56. For publisher information, see AACRAT. Volume(issue)/page/year: 25,221,1946

HS Code	2918990090

89-55-4

108-24-7

~86%

1503-53-3

Literature: Sharma, Horrick; Patil, Shivaputra; Sanchez, Tino W.; Neamati, Nouri; Schinazi, Raymond F.; Buolamwini, John K. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 6 p. 2030 - 2045

89-55-4

~87%

1503-53-3

Literature: Kowa Co., Ltd. Patent: US6136848 A1, 2000 ;

89-55-4

75-36-5

~96%

1503-53-3

Literature: TRANSTECH PHARMA, INC. Patent: WO2004/14844 A2, 2004 ; Location in patent: Page 203 ; WO 2004/014844 A2

Precursor 3
89-55-4 108-24-7 75-36-5
DownStream 4
30779-63-6 7120-43-6 6329-74-4 5485-91-6

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

1503-53-3	1503-54-4
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