384380-52-3
384380-52-3 structure
- Name: Abacavir carboxylate
- Chemical Name: (1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-ene-1-carboxylic acid
- CAS Number: 384380-52-3
- Molecular Formula: C14H16N6O2
- Molecular Weight: 300.31600
- Create Date: 2016-05-10 07:07:46
- Modify Date: 2023-01-06 13:03:14
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Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir. It is formed from abacavir via reactive aldehyde intermediates that can form adducts with proteins on valine residues.
| Name | (1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-ene-1-carboxylic acid |
|---|---|
| Synonyms |
(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-carboxylic Acid
abacavir carboxylate 2269W 5'-oxoabacavir abacavir 5'-carboxylate (1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-ene-1-carboxylic acid abacavir carboxylic acid |
| Molecular Formula | C14H16N6O2 |
|---|---|
| Molecular Weight | 300.31600 |
| Exact Mass | 300.13300 |
| PSA | 119.68000 |
| LogP | 1.18770 |