65189-64-2

65189-64-2 structure

Name: (D-Ala2)-Leu-Enkephalin amide
Chemical Name: (2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
CAS Number: 65189-64-2
Molecular Formula: C₂₉H₄₀N₆O₆
Molecular Weight: 568.66400
Catalog: Research Areas Neurological Disease
Create Date: 2018-06-22 17:51:09
Modify Date: 2024-01-04 10:41:15
[D-Ala2] Leu-Enkephalinamide is an enkephalin analog. [D-Ala2] Leu-Enkephalinamide has great corneal permeability and analgesic effect. [D-Ala2] Leu-Enkephalinamide can be used for the research of ocular diseases[1][2].

Name	(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Synonyms	Leu-enkephalinamide,ala(2) enkephalinamide-Leu,Ala(2) 2-Ala-leu-enkephalinamide Enkephalinamide-leu,alanine(2) DALEA Leucine-enkephalinamide,ala(2) DALE (D-Ala2)-Leu-Enkephalin amide Ala(2)-Enkephalinamide-Leu

Description	[D-Ala2] Leu-Enkephalinamide is an enkephalin analog. [D-Ala2] Leu-Enkephalinamide has great corneal permeability and analgesic effect. [D-Ala2] Leu-Enkephalinamide can be used for the research of ocular diseases[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	[D-Ala2] Leu-Enkephalinamide (MEA) (1.0 mM; 10-240 min) has great corneal permeability in vitro[1].
In Vivo	D-Ala2-Leu-enkephalinamide (s.c.) is also enhanced in morphine-dependent animals[2].