4199-10-4
4199-10-4 structure
- Name: (S)-(-)-PROPRANOLOL HYDROCHLORIDE
- Chemical Name: (s)-(-)-propranolol hydrochloride
- CAS Number: 4199-10-4
- Molecular Formula: C16H22ClNO2
- Molecular Weight: 295.80400
- Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
- Create Date: 2018-07-16 07:45:12
- Modify Date: 2024-01-05 07:09:18
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(S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[2].
| Name | (s)-(-)-propranolol hydrochloride |
|---|---|
| Synonyms |
dl-propranololHClbp
PROPRANOLOL HCL dl-propranolol hcl dl-propranololhydrochloridebp PENTAPROPANOLOLHYDROCHLORIDE Sazetidine A dihydrochloride DL-PROPRANOLOL HYDROCHLORIDE EINECS 224-096-0 PROPANOLOL HYDROCHLORIDE L-Propranololhydrochlorid MFCD00064547 |
| Description | (S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[2]. |
|---|---|
| Related Catalog | |
| Target |
log Kd: -8.16 (β1-adrenergic receptor) log Kd: -9.08 (β2-adrenergic receptor) log Kd: -6.93 (β3-adrenergic receptor)[1] |
| References |
| Boiling Point | 434.9ºC at 760mmHg |
|---|---|
| Melting Point | 193-195ºC(lit.) |
| Molecular Formula | C16H22ClNO2 |
| Molecular Weight | 295.80400 |
| Flash Point | 216.8ºC |
| Exact Mass | 295.13400 |
| PSA | 41.49000 |
| LogP | 3.77040 |
| Appearance | powder |
| Storage condition | 2-8°C |
| Water Solubility | ethanol: 10 mg/mL |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H332 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R20/21/22 |
| Safety Phrases | 36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2906199090 |
| Precursor 8 | |
|---|---|
| DownStream 0 | |
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |