13411-16-0

13411-16-0 structure

Name: Nifurpirinol
Chemical Name: [6-[(E)-2-(5-nitrofuran-2-yl)ethenyl]pyridin-2-yl]methanol
CAS Number: 13411-16-0
Molecular Formula: C₁₂H₁₀N₂O₄
Molecular Weight: 246.21900
Catalog: analytical chemistry Analytical reagent Ion chromatography reagent
Create Date: 2018-08-24 14:17:45
Modify Date: 2024-01-14 10:41:07
Nifurpirinol (P-7138) is a nitroaromatic antibiotic and acts as a novel substrate for the bacterial nitroreductase (NTR) enzyme. Nifurpirinol is a more potent prodrug compared to Metronidazole to trigger cell-ablation in nitroreductase expressing transgenic models[1].

Name	[6-[(E)-2-(5-nitrofuran-2-yl)ethenyl]pyridin-2-yl]methanol
Synonyms	Furanace Furpirinol Furpirinol Furpyrinol {6-[2-(5-Nitro-2-furanyl)vinyl]-2-pyridinyl}methanol Furpyrinol Nifurpirinol Furanace-10

Description	Nifurpirinol (P-7138) is a nitroaromatic antibiotic and acts as a novel substrate for the bacterial nitroreductase (NTR) enzyme. Nifurpirinol is a more potent prodrug compared to Metronidazole to trigger cell-ablation in nitroreductase expressing transgenic models[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: bacterial nitroreductase (NTR) enzyme[1]
References	[1]. David Bergemann, et al. Nifurpirinol: A more potent and reliable substrate compared to metronidazole for nitroreductase-mediated cell ablations. Wound Repair Regen

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IDZAAW Japanese Journal of Genetics. Idengaku Zasshi. (Genetics Soc. of Japan, 111 Tanida, Mishima, Shizuoka-ken, Japan) V.1- 1921- Volume(issue)/page/year: 48,291,1973

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xi
Risk Phrases	36
Safety Phrases	26
RIDADR	NONH for all modes of transport
RTECS	UT5023000
HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%