2470130-12-0

2470130-12-0 structure

2470130-12-0 structure

Name: Sulfamethizole-d4-1
Chemical Name: Sulfamethizole-d4-1
CAS Number: 2470130-12-0
Molecular Formula: C₉H₆D₄N₄O₂S₂
Molecular Weight: 274.36
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2023-05-05 16:51:51
Modify Date: 2024-01-21 08:11:18
Sulfamethizole-d4-1 is the deuterium labeled Sulfamethizole[1]. Sulfamethizole is a sulfathiazole antibacterial agent[2][3].

Name	Sulfamethizole-d4-1

Description	Sulfamethizole-d4-1 is the deuterium labeled Sulfamethizole[1]. Sulfamethizole is a sulfathiazole antibacterial agent[2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Watanabe, H. and J.W. Hastings, Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine. Biochim Biophys Acta, 1990. 1017(3): p. 229-34. [3]. Kerrn, M.B., N. Frimodt-Moller, and F. Espersen, Effects of sulfamethizole and amdinocillin against Escherichia coli strains (with various susceptibilities) in an ascending urinary tract infection mouse model. Antimicrob Agents Chemother, 2003. 47(3): p. 1002-9.

Molecular Formula	C₉H₆D₄N₄O₂S₂
Molecular Weight	274.36