1236141-96-0

1236141-96-0 structure

Name: Microtubule inhibitor 3
Chemical Name: Microtubule inhibitor 3
CAS Number: 1236141-96-0
Molecular Formula: C₂₆H₂₃FN₄O₃
Molecular Weight: 458.48
Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
Create Date: 2022-06-26 17:28:30
Modify Date: 2024-01-07 14:40:55
Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.

Name	Microtubule inhibitor 3

Description	Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Ding Z,et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435.

Molecular Formula	C₂₆H₂₃FN₄O₃
Molecular Weight	458.48