2459892-41-0

2459892-41-0 structure

Name: Antiproliferative agent-5
Chemical Name: Antiproliferative agent-5
CAS Number: 2459892-41-0
Molecular Formula: C₂₈H₂₁BrN₈OS
Molecular Weight: 597.49
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2022-07-01 18:53:13
Modify Date: 2024-01-31 10:39:12
Antiproliferative against-5 (compound 4o) can significantly and irreversibly inhibit proliferation of gastric cancer cells. Antiproliferative against-5 causes the G2/M phase arrest, and induces ROS accumulation and activation of autophagy. Antiproliferative against-5 can be used for researching anticancer[1].

Name	Antiproliferative agent-5

Description	Antiproliferative against-5 (compound 4o) can significantly and irreversibly inhibit proliferation of gastric cancer cells. Antiproliferative against-5 causes the G2/M phase arrest, and induces ROS accumulation and activation of autophagy. Antiproliferative against-5 can be used for researching anticancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Signaling Pathways >> Autophagy >> Autophagy
Target	ROS, Autophagy[1]
References	[1]. Wang S, et al. Discovery of new [1,2,4] Triazolo[1,5-a]Pyrimidine derivatives that Kill gastric cancer cells via the mitochondria pathway. Eur J Med Chem. 2020;203:112630.

Molecular Formula	C₂₈H₂₁BrN₈OS
Molecular Weight	597.49