1134182-00-5

1134182-00-5 structure

1134182-00-5 structure

Name: Telbivudine-d4
Chemical Name: Telbivudine-d4
CAS Number: 1134182-00-5
Molecular Formula: C₁₀H₁₀D₄N₂O₅
Molecular Weight: 246.25
Catalog: Signaling Pathways Anti-infection HBV
Create Date: 2022-07-30 01:53:25
Modify Date: 2024-01-14 17:49:46
Telbivudine-d4 is deuterium labeled Telbivudine. Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication[1].

Name	Telbivudine-d4

Description	Telbivudine-d4 is deuterium labeled Telbivudine. Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Kim JW, et al. Telbivudine: a novel nucleoside analog for chronic hepatitis B. Ann Pharmacother. 2006;40(3):472-478. [3]. Zobel T, et al. Telbivudine Reduces Parvovirus B19-Induced Apoptosis in Circulating Angiogenic Cells. Viruses. 2019;11(3):227. Published 2019 Mar 6.

Molecular Formula	C₁₀H₁₀D₄N₂O₅
Molecular Weight	246.25