DC Chemicals Limited
China
Product Name: Dual AChE-MAO B-IN-2
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1801157-64-1

1801157-64-1 structure

1801157-64-1 structure

Name: Dual AChE-MAO B-IN-2
Chemical Name: Dual AChE-MAO B-IN-2
CAS Number: 1801157-64-1
Molecular Formula: C₂₆H₂₅NO₄
Molecular Weight: 415.48
Create Date: 2022-05-20 08:16:49
Modify Date: 2024-01-11 15:52:14
Dual AChE-MAO B-IN-2 is a potent AChE and MAO B dual inhibitor with IC50s of 0.12 µM and 0.01 µM for b>AChE and MAO B, respectively. Dual AChE-MAO B-IN-2 has the potential for the research of Alzheimer’s disease[1].

Name	Dual AChE-MAO B-IN-2

Description	Dual AChE-MAO B-IN-2 is a potent AChE and MAO B dual inhibitor with IC50s of 0.12 µM and 0.01 µM for b>AChE and MAO B, respectively. Dual AChE-MAO B-IN-2 has the potential for the research of Alzheimer’s disease[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	MAO-B:4.5 μM (Ki)
In Vitro	Dual AChE-MAO B-IN-2 (compound 1) shows a +5.5 °C increase in the MAO B enzyme Tm value[1].
References	[1]. Ekström F, et al. Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures. ACS Med Chem Lett. 2022, 13(3):499-506.

Molecular Formula	C₂₆H₂₅NO₄
Molecular Weight	415.48