1346597-29-2

1346597-29-2 structure

1346597-29-2 structure

Name: Loracarbef-d5
Chemical Name: Loracarbef-d5
CAS Number: 1346597-29-2
Molecular Formula: C₁₆H₁₁D₅ClN₃O₄
Molecular Weight: 354.80
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2021-11-02 17:15:02
Modify Date: 2024-01-10 15:13:06
Loracarbef-d5 is the deuterium labeled Loracarbef. Loracarbef, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class[1][2].

Name	Loracarbef-d5

Description	Loracarbef-d5 is the deuterium labeled Loracarbef. Loracarbef, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. M Hu, et al. Mechanisms of Transport of Quinapril in Caco-2 Cell Monolayers: Comparison With Cephalexin. Pharm Res. 1995 Aug;12(8):1120-5. [3]. J W Dyke, et al. Antimicrobial Activity of New Antibiotics Against Bacterial Isolates From a Community Hospital. Chemotherapy. Sep-Oct 1993;39(5):315-21.

Molecular Formula	C₁₆H₁₁D₅ClN₃O₄
Molecular Weight	354.80