1052678-30-4

1052678-30-4 structure

Name: Propargyl-PEG3-phosphonic acid ethyl ester
Chemical Name: Propargyl-PEG3-phosphonic acid diethyl ester
CAS Number: 1052678-30-4
Molecular Formula: C₁₃H₂₅O₆P
Molecular Weight: 308.31
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-14 20:08:58
Modify Date: 2024-01-15 21:47:58
Propargyl-PEG3-phosphonic acid diethyl ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG3-phosphonic acid diethyl ester

Description	Propargyl-PEG3-phosphonic acid diethyl ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Thorsten Heidelberg, et al. Oligo-ethylene glycol based phosphonate surface modification reagents and use thereof. WO2015065168A1