2209053-93-8
2209053-93-8 structure
- Name: PDGFRα kinase inhibitor 1
- Chemical Name: PDGFRα kinase inhibitor 1
- CAS Number: 2209053-93-8
- Molecular Formula: C34H34N8O2
- Molecular Weight: 586.69
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PDGFR
- Create Date: 2019-03-03 10:44:07
- Modify Date: 2024-01-09 19:27:58
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PDGFRα kinase inhibitor 1 is a highly selective type II PDGFRα kinase inhibitor with IC50s of 132 nM and 6115 nM for PDGFRα and PDGFRβ, respectively[1].
| Name | PDGFRα kinase inhibitor 1 |
|---|
| Description | PDGFRα kinase inhibitor 1 is a highly selective type II PDGFRα kinase inhibitor with IC50s of 132 nM and 6115 nM for PDGFRα and PDGFRβ, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
PDGFRα:132 nM (IC50) PDGFRβ:6115 nM (IC50) |
| In Vitro | PDGFRα kinase inhibitor 1 (CHMFL-PDGFR-159, Compound 15i) exhibits weak inhibition to DDR1 kinase (IC50: 2462±126 nM)[1]. |
| References |
| Molecular Formula | C34H34N8O2 |
|---|---|
| Molecular Weight | 586.69 |