1245792-51-1
1245792-51-1 structure
- Name: BCI
- Chemical Name: (2E)-2-Benzylidene-3-(cyclohexylamino)-1-indanone
- CAS Number: 1245792-51-1
- Molecular Formula: C22H23NO
- Molecular Weight: 317.424
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
- Create Date: 2018-06-02 06:13:55
- Modify Date: 2024-01-11 10:01:51
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BCI is an allosteric inhibitor of dual specificity phosphatase (DUSP). BCI specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI does not inhibit DUSP5[1].
| Name | (2E)-2-Benzylidene-3-(cyclohexylamino)-1-indanone |
|---|---|
| Synonyms |
(2E)-2-Benzylidene-3-(cyclohexylamino)-1-indanone
1H-Inden-1-one, 3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-, (2E)- MFCD20232928 |
| Description | BCI is an allosteric inhibitor of dual specificity phosphatase (DUSP). BCI specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI does not inhibit DUSP5[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 484.6±45.0 °C at 760 mmHg |
| Molecular Formula | C22H23NO |
| Molecular Weight | 317.424 |
| Flash Point | 161.3±28.9 °C |
| Exact Mass | 317.177979 |
| LogP | 5.65 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.625 |
| Hazard Codes | Xi |
|---|