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153364-63-7

153364-63-7 structure
153364-63-7 structure
  • Name: m-PEG3-0-benzaldehyde
  • Chemical Name: 4-{2-[2-(2-Methoxyethoxy)ethoxy]ethoxy}benzaldehyde
  • CAS Number: 153364-63-7
  • Molecular Formula: C14H20O5
  • Molecular Weight: 268.306
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-20 19:59:55
  • Modify Date: 2024-01-15 09:29:12
  • m-PEG3-0-benzaldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 4-{2-[2-(2-Methoxyethoxy)ethoxy]ethoxy}benzaldehyde
Synonyms Benzaldehyde, 4-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-
4-{2-[2-(2-Methoxyethoxy)ethoxy]ethoxy}benzaldehyde
MFCD22683279
Description m-PEG3-0-benzaldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 383.8±32.0 °C at 760 mmHg
Molecular Formula C14H20O5
Molecular Weight 268.306
Flash Point 168.4±25.2 °C
Exact Mass 268.131073
LogP 0.65
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.510