1036204-60-0
1036204-60-0 structure
- Name: Propargyl-PEG5-OH
- Chemical Name: 3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol
- CAS Number: 1036204-60-0
- Molecular Formula: C13H24O6
- Molecular Weight: 276.326
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-26 20:18:55
- Modify Date: 2024-02-02 18:18:50
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Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
| Name | 3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol |
|---|---|
| Synonyms | 3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol |
| Description | Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
[1]. Robert Zamboni, et al. Raf-degrading conjugate compounds. WO2018200981A1. |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 368.1±37.0 °C at 760 mmHg |
| Molecular Formula | C13H24O6 |
| Molecular Weight | 276.326 |
| Flash Point | 176.4±26.5 °C |
| Exact Mass | 276.157288 |
| LogP | -1.68 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.461 |
| Storage condition | 2-8°C |