1428629-71-3
1428629-71-3 structure
- Name: Propargyl-PEG3-NHS ester
- Chemical Name: 1-[(3-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}propanoyl)oxy]-2,5-pyrrolidinedione
- CAS Number: 1428629-71-3
- Molecular Formula: C14H19NO7
- Molecular Weight: 313.303
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-07-19 14:28:50
- Modify Date: 2024-01-10 15:28:04
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Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Name | 1-[(3-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}propanoyl)oxy]-2,5-pyrrolidinedione |
|---|---|
| Synonyms |
1-[(3-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}propanoyl)oxy]-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-[1-oxo-3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]propoxy]- MFCD23726610 |
| Description | Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
[1]. Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 427.2±55.0 °C at 760 mmHg |
| Molecular Formula | C14H19NO7 |
| Molecular Weight | 313.303 |
| Flash Point | 212.1±31.5 °C |
| Exact Mass | 313.116150 |
| LogP | -1.96 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.507 |
| Hazard Codes | Xi |
|---|