Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Isotanshinone IIA
Price: ￥3928.0/5mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Isotanshinone IIA
Price: $1050.0/100mg $2100.0/250mg $4200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Isotanshinone IIA
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

20958-15-0

20958-15-0 structure

20958-15-0 structure

Name: Isotanshinone IIA
Chemical Name: isotanshinone IIA
CAS Number: 20958-15-0
Molecular Formula: C₁₉H₁₈O₃
Molecular Weight: 294.34400
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2018-07-03 14:31:18
Modify Date: 2024-01-05 18:46:57
Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.

Name	isotanshinone IIA
Synonyms	4,4,8-Trimethyl-2,3-dihydro-1H,4H-10-oxa-cyclopenta[b]phenanthrene-7,11-dione Isotanshinon-II isotanshinone II

Description	Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Metabolic Disease Natural Products >> Others
Target	IC50: 11.4 μM (PTP1B)[1].
References	[1]. Han YM, et al. PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza. Biol Pharm Bull. 2005 Sep;28(9):1795-7.

Boiling Point	471.1±45.0 °C(Predicted)
Molecular Formula	C₁₉H₁₈O₃
Molecular Weight	294.34400
Exact Mass	294.12600
PSA	47.28000
LogP	3.97730

Hazard Codes	Xi