453560-74-2
453560-74-2 structure
- Name: 2-Methoxy-4-nitro-1-(trifluoromethyl)benzene
- Chemical Name: 2-Methoxy-4-nitro-1-(trifluoromethyl)benzene
- CAS Number: 453560-74-2
- Molecular Formula: C8H6F3NO3
- Molecular Weight: 221.13300
- Create Date: 2018-12-29 18:04:30
- Modify Date: 2024-01-02 21:22:18
| Name | 2-Methoxy-4-nitro-1-(trifluoromethyl)benzene |
|---|---|
| Synonyms |
5-nitro-2-trifluoromethylanisole
methoxynitrotrifluoromethylbenzene AD-0764 2-methoxy-4-nitro-1-trifluoromethyl-benzene |
| Molecular Formula | C8H6F3NO3 |
|---|---|
| Molecular Weight | 221.13300 |
| Exact Mass | 221.03000 |
| PSA | 55.05000 |
| LogP | 3.14540 |
|
~43%
453560-74-2 |
| Literature: Potashman, Michele H.; Bready, James; Coxon, Angela; Demelfi Jr., Thomas M.; DiPietro, Lucian; Doerr, Nicholas; Elbaum, Daniel; Estrada, Juan; Gallant, Paul; Germain, Julie; Gu, Yan; Harmange, Jean-Christophe; Kaufman, Stephen A.; Kendall, Rick; Kim, Joseph L.; Kumar, Gondi N.; Long, Alexander M.; Neervannan, Seshadri; Patel, Vinod F.; Polverino, Anthony; Rose, Paul; Van Der Plas, Simon; Whittington, Douglas; Zanon, Roger; Zhao, Huilin Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4351 - 4373 |
|
~73%
453560-74-2 |
| Literature: Talamas, Francisco X.; Abbot, Sarah C.; Anand, Shalini; Brameld, Ken A.; Carter, David S.; Chen, Jun; Davis, Dana; De Vicente, Javier; Fung, Amy D.; Gong, Leyi; Harris, Seth F.; Inbar, Petra; Labadie, Sharada S.; Lee, Eun K.; Lemoine, Remy; Le Pogam, Sophie; Leveque, Vincent; Li, Jim; McIntosh, Joel; Najera, Isabel; Park, Jaehyeon; Railkar, Aruna; Rajyaguru, Sonal; Sangi, Michael; Schoenfeld, Ryan C.; Staben, Leanna R.; Tan, Yunchou; Taygerly, Joshua P.; Villasenor, Armando G.; Weller, Paul E. Journal of Medicinal Chemistry, 2014 , vol. 57, # 5 p. 1914 - 1931 |
|
~51%
453560-74-2 |
| Literature: Brotherton-Pleiss, Christine E.; Caroon, Joan Marie; Lopez-Tapia, Francisco Javier Patent: US2010/160388 A1, 2010 ; Location in patent: Page/Page column 64-65 ; US 20100160388 A1 |
|
~%
453560-74-2 |
| Literature: VERTEX PHARMACEUTICALS INCORPORATED Patent: US2010/168094 A1, 2010 ; Location in patent: Page/Page column 69; 70 ; US 20100168094 A1 |
|
~%
453560-74-2 |
| Literature: AMGEN INC Patent: WO2004/85425 A1, 2004 ; Location in patent: Page 98-99 ; WO 2004/085425 A1 |
|
~64%
453560-74-2 |
| Literature: Hafner, Andreas; Braese, Stefan Advanced Synthesis and Catalysis, 2013 , vol. 355, # 5 p. 996 - 1000 |
| Precursor 6 | |
|---|---|
| DownStream 3 | |
