142816-70-4

142816-70-4 structure

Name: 4-N-benzoylgeMcitabine
Chemical Name: N4-benzoyl-2'-deoxy-2',2'-difluorocytidine
CAS Number: 142816-70-4
Molecular Formula: C₁₆H₁₅F₂N₃O₅
Molecular Weight: 367.30
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-07-03 13:49:03
Modify Date: 2024-01-10 18:41:17
N4-Benzoyl-2’-deoxy-2’,2’-diflurocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	N4-benzoyl-2'-deoxy-2',2'-difluorocytidine
Synonyms	N-benzoyl-2'-deoxy-2',2'-difluorocytidine 4-N-benzoylgemcitabine N-benzoyl-2'-deoxy-2',2'-difluorocytidine hydrochloride N-Bz-Gemcitabine

Description	N4-Benzoyl-2’-deoxy-2’,2’-diflurocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.