2149-70-4

2149-70-4 structure

Name: H-Arg(NO2)-OH
Chemical Name: N'-Nitro-L-arginine
CAS Number: 2149-70-4
Molecular Formula: C₆H₁₃N₅O₄
Molecular Weight: 219.199
Catalog: Biochemical Amino acids and their derivatives Arginine derivatives
Create Date: 2018-06-22 01:23:07
Modify Date: 2024-01-02 19:43:19
Nitroarginine, or Nω-nitro-L-arginine, is a nitro derivative of the amino acid arginine. It is an inhibitor of nitric oxide synthase and hence a vaso-constrictor and coronary constrictor. As such, it finds widespread use as a biochemical tool in the study of nitric oxide and its biological effects. Nitroarginine has been used in research studying coronary constriction, in the presence of midazolam vasodilatation was unaffected by nitroarginine. Nitroarginine is currently in clinical trials for treating patients with advanced solid tumors.

Name	N'-Nitro-L-arginine
Synonyms	(S)-2-Amino-5-(3-nitroguanidino)pentanoic acid L-Ornithine, N-[(E)-imino(nitroamino)methyl]- ARG(NO2) L-NNA N-ω-NITRO-L-ARGININE L-NOARG Nω-Nitro-L-arginine (S)-2-Aminobut-3-enoic acid H-Arg(NO2)-OH L-Ornithine, N5-(imino(nitroamino)methyl)- H-ARG(NO2)-OME Nω-Nitro-L-arginine (L-NNA) NG-nitro-L-arginine EINECS 218-418-9 MFCD00007033 NG-NO2-L-ARG L-NA,L-NNA L-NA L-NO2ARG nitroarginine Nomega-nitro-L-arginine L-NNA N5-(Nitroamidino)-L-2,5-diaminopentanoic acid NG-NO2-L-Arg L-NG-nitroarginine N-(N-Nitrocarbamimidoyl)-L-ornithine

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
Risk Phrases	R22
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

74-79-3

2149-70-4

Literature: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 224, p. 40,43

1119-34-2

2149-70-4

2188-18-3

2149-70-4

Literature: Chemische Berichte, , vol. 97, p. 3312 - 3316 Bulletin of the Chemical Society of Japan, , vol. 38, p. 1148 - 1157

157-06-2

2149-70-4

Literature: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 72, p. 489