204633-98-7

204633-98-7 structure

Name: L-Asparagine-N-Fmoc,N-beta-trityl-15N2
Chemical Name: l-asparagine-n-fmoc, n-beta-trityl (15n2)
CAS Number: 204633-98-7
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Cancer
Create Date: 2016-12-09 09:35:59
Modify Date: 2024-01-09 10:33:32
L-Asparagine-N-Fmoc,N-beta-trityl-15N2 is a 15N-labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

Name	l-asparagine-n-fmoc, n-beta-trityl (15n2)

Description	L-Asparagine-N-Fmoc,N-beta-trityl-15N2 is a 15N-labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
Related Catalog	Research Areas >> Cancer
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-240. [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-240.

No Any Chemical & Physical Properties