- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Deoxyribonuclease
- Price: ￥238.0/100mg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Deoxyribonuclease
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: 9003-98-9,Deoxyribonuclease
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
9003-98-9
9003-98-9 structure
- Name: Deoxyribonuclease
- Chemical Name: Deoxyribonuclease
- CAS Number: 9003-98-9
- Molecular Formula:
- Molecular Weight:
- Catalog: Biochemical Enzymes and coenzymes
- Create Date: 2018-02-07 08:00:00
- Modify Date: 2024-01-04 19:53:01
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Deoxyribonuclease (DNase) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer[1].
| Name | Deoxyribonuclease |
|---|---|
| Synonyms |
Alkaline DNase
Alkaline deoxyribonuclease DNA depolymerase DNA endonuclease DNA nuclease DNAase DNase Deoxyribonuclease A Deoxyribonuclease I Deoxyribonucleic phosphatase Desoxyribonuclease Dornase Pancreatic deoxyribonuclease Pancreatic dornase |
| Description | Deoxyribonuclease (DNase) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Deoxyribonuclease (0.1 U; i.p.; once daily for 3 days) inhibits liver metastasis, besides results in a greater prolongation of the survival period by combining surgical removal of the primary tumour mass[1]. Animal Model: Female BALB/c x DBA/2 mice with murine tumour L5178Y-ML cells subcutaneous injection[1] Dosage: 0.1 U per mouse Administration: Intravenous injection; 0.1 U; once daily for three days Result: Reduced liver weight from 2.26 to 1.55 g, affected the intensity of liver metastasis, reduced the numbers and sizes of metastatic and affected tumour cell arrest. Animal Model: Female BALB/c x DBA/2 mice with murine tumour and surgical removal of subcutaneous tumours[1] Dosage: 0.1 U per mouse Administration: Intravenous injection; 0.1 U; once daily for 3 days either before or after primary tumour removal Result: Significantly prolongated survival after tumour cell inoculation compared to the untreated group. |
| Density | 100 g/mL at 20 °C |
|---|---|
| Appearance | solution (clear, colorless) | white |
| Storage condition | −20°C |
| Water Solubility | Soluble in 0.15 M sodium chloride (5.0mg/L) clear. |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 23-24/25-22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | RF0750000 |