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56-87-1

56-87-1 structure
56-87-1 structure
  • Name: L-Lysine
  • Chemical Name: L-lysine
  • CAS Number: 56-87-1
  • Molecular Formula: C6H14N2O2
  • Molecular Weight: 146.188
  • Catalog: Biochemical Common amino acids and protein drugs
  • Create Date: 2018-08-16 19:57:44
  • Modify Date: 2024-01-02 08:14:23
  • L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].

Name L-lysine
Synonyms L-lys
Lisina [Spanish]
6-Amino-L-norleucine
(+)-S-Lysine
Lys
L-Lysine (9CI)
(l)-lysine
(S)-(+)-Lysine
Aminutrin
Lysine acid
(S)-a,e-Diaminocaproic Acid
Lysinum [Latin]
(S)-lysine
Lysine
2,6-Diaminohexanoic acid, (S)-
FEMA 3847
(S)-2,6-diamino-Hexanoic acid
L-Lysine
Lysine, L-
MFCD00064433
EINECS 200-294-2
H-Lys-OH
L-lysine zwitterion
Description L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].
Related Catalog
Target

L-lysine (150 mg/kg) promotes, but not initiates, bladder cancer. The administration of L-lysine to rats submitted to colovesical cystoplasty accelerates the development of transitional metaplasia of the intestinal epithelium[1]. L-lysine (10 mg/kg) treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity[2].

References

[1]. Santos AMD, et al. Transitional metaplasia in intestinal epithelium of rats submitted to intestinal cystoplasty and treatment with L -lysine. Acta Cir Bras. 2017 Apr;32(4):297-306.

[2]. Al-Malki AL. Suppression of acute pancreatitis by L-lysine in mice. BMC Complement Altern Med. 2015 Jun 23;15:193.

Density 1.1±0.1 g/cm3
Boiling Point 311.5±32.0 °C at 760 mmHg
Melting Point 215 °C (dec.)(lit.)
Molecular Formula C6H14N2O2
Molecular Weight 146.188
Flash Point 142.2±25.1 °C
Exact Mass 146.105530
PSA 89.34000
LogP -1.04
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.503
Storage condition Store at RT.
Stability Stable. Incompatible with strong oxidizing agents.
Water Solubility H2O: 0.1 g/mL, clear, colorless

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OL5540000
CHEMICAL NAME :
Lysine, L-
CAS REGISTRY NUMBER :
56-87-1
BEILSTEIN REFERENCE NO. :
1722531
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C6-H14-N2-O2
MOLECULAR WEIGHT :
146.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
138 gm/kg
SEX/DURATION :
female 5-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
72450 mg/kg
SEX/DURATION :
female 10-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
90450 mg/kg
SEX/DURATION :
female 10-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
81 gm/kg
SEX/DURATION :
female 10-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
44 gm/kg
SEX/DURATION :
female 5-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS OL5540000
HS Code 2922411000
HS Code 2922411000
Summary HS: 2922411000. 2,6-diaminohexanoic acid. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:ab(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tarrif:5.0%. general tariff:20.0%