71897-07-9

71897-07-9 structure

Name: 2-Phenyl-6,7-dimethylquinoxaline
Chemical Name: 6,7-dimethyl-2-phenylquinoxaline
CAS Number: 71897-07-9
Molecular Formula: C₁₆H₁₄N₂
Molecular Weight: 234.296
Catalog: Biochemical Amino acids and their derivatives Tyrosine derivatives
Create Date: 2018-07-20 13:00:53
Modify Date: 2024-01-02 17:10:00
AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG 1295 reduces neointimal formation in aortic allograft vasculopathy by inhibition of PDGFR-beta-triggered tyrosine phosphorylation[1][2].

Name	6,7-dimethyl-2-phenylquinoxaline
Synonyms	AG 1295 2-Phenyl-6,7-dimethylquinoxaline F1284-0835 TYRPHOSTIN AG 1295 6,7-Dimethyl-2-phenylquinoxaline 6,7-dimethyl-2-phenyl-quinoxaline Quinoxaline, 6,7-dimethyl-2-phenyl- 6,7-Dimethyl-2-phenyl-chinoxalin

Description	AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG 1295 reduces neointimal formation in aortic allograft vasculopathy by inhibition of PDGFR-beta-triggered tyrosine phosphorylation[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR
Target	PDGFR[1]
References	[1]. Zheng Y, et al. Platelet-derived growth factor receptor kinase inhibitor AG1295 and inhibition of experimental proliferative vitreoretinopathy. Jpn J Ophthalmol. 2003 Mar-Apr;47(2):158-65. [2]. Inhibition of aortic allograft vasculopathy by local delivery of platelet-derived growth factor receptor tyrosine-kinase blocker AG-1295. Transplantation. 2002 Nov 15;74(9):1335-41.

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%