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24292-52-2

24292-52-2 structure
24292-52-2 structure
  • Name: Hesperidin methylchalcone
  • Chemical Name: Hesperidin methylchalcone
  • CAS Number: 24292-52-2
  • Molecular Formula: C29H36O15
  • Molecular Weight: 624.587
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-03-31 08:00:00
  • Modify Date: 2024-01-03 14:59:19
  • Hesperidin methylchalcone (Hesperidin methyl chalcone) inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone inhibits inflammation and pain. Hesperidin methylchalcone exhibits vasoprotective activity[1].

Name Hesperidin methylchalcone
Synonyms 2-Propen-1-one, 1-[4-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-
3-Hydroxy-4-[3-(3-hydroxy-4-methoxyphenyl)acryloyl]-5-methoxyphenyl 6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
HESPERIDIN METHYL CHALCONE
HESPERIDIN METHYL CHALCONE*PRACTICAL GRA DE
EINECS 246-128-2
MFCD00010438
Hesperidine Methyl Chalcone
(e)-osyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)
Description Hesperidin methylchalcone (Hesperidin methyl chalcone) inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone inhibits inflammation and pain. Hesperidin methylchalcone exhibits vasoprotective activity[1].
Related Catalog
Target

NF-κB

References

[1]. Pinho-Ribeiro FA, et al. Protective effects of the flavonoid hesperidin methyl chalcone in inflammation and pain in mice: role of TRPV1, oxidative stress, cytokines and NF-κB. Chem Biol Interact. 2015 Feb 25;228:88-99.

Density 1.6±0.1 g/cm3
Boiling Point 953.0±65.0 °C at 760 mmHg
Melting Point 120 °C (dec.)(lit.)
Molecular Formula C29H36O15
Molecular Weight 624.587
Flash Point 309.5±27.8 °C
Exact Mass 624.205444
PSA 234.29000
LogP 1.86
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.672
Storage condition 2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FL7085000
CHEMICAL NAME :
Chalcone, 2',3,4'-trihydroxy-4,6'-dimethoxy-, 4'-(6-O-(6-deoxy-alpha-L-mannopyranosyl)- beta-D-glucopyranoside)
CAS REGISTRY NUMBER :
24292-52-2
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C29-H36-O15
MOLECULAR WEIGHT :
624.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3 gm/kg
SEX/DURATION :
male 10 day(s) pre-mating female 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - parturition
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 118,657,1953
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS FL7085000